Luigi Preziosi - Dept. Mathematical Sciences, Politecnico di Torino
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Motion of Cells and Aggregates
Phase contrast time-lapse microscopy of in vitro dissociation and migration of ARO cells, grown in 10% fetal calf serum and incubated in the presence of 100 U/ml of hepatocyte growth factor (more info). Simulation of cell-cell dissociation process of ARO cells under the action of hepatocyte growth factor (more info). In vitro branching morphogenes of a colony of MLP-29 cells, incubated for 24 h in DMEM-1% fetal calf serum, containing recombinant hepatocyte growth factor, diluted to the final concentration of 100ng/ml (more info). Simulation of branching morphogenesis of a clump of MLP-29 cells under the action of hepatocyte growth factor (more info).
Simulation of wound-healing assay of two masses of 120 ARO cells (more info). Cell motion by a compartimentalized Cellular Potts Model. (more info). Invasion of a ovarian tumour cell through the mesothelium (more info). Invasion of a multicellular spheroid of an ovary tumour through the mesothelium (more info).
Vasculogenesis
First moments of the formation of a capillary network by human microvascular endothelial cells plated (125 cells/mm2) on Matrigel (more info). Contact me for a longer version (too big to be put on the web). Effect of the interaction with the Matrigel on the process of formation of the capillary network by vasculogenesis (more info).
Tumour Growth
Growth of two colonies of WiDr cell lines which differ in their motility. Evolution of the volume ratios (more info). Growth of two colonies of WiDr cell lines which differ in their motility. Evolution of the growth rate (more info). Growth of a tumor cord along a capillary on the x-axis. Distribution of oxygen. Cells in the blue region are hypoxic. The line represents the tumor border. Growth of a tumor cord along a capillary on the x-axis. Volume ratio of tumor and host cells. The line represents the tumor border.
Growth of a tumor on a vascular network. Distribution of oxygen (more info). Tumor cord growth with aerobic and anaerobic populations. The starvation limits for the two populations are identified by the dashed line. The thick line represents the tumor border. Color/darkness shows the deficit of ATP for aerobic cells, i.e., the severity of hypoxia (more info). Volume fraction of anaerobic cells and tissue velocity. The starvation limits for the two populations are identified by the dashed line. The thick line represents the tumor border (more info).
Engineering Applications
Instability of a viscous liquid (soybean oil) coating the inside of a rotating cylinder. Simulation of an avalanche sliding down a curved slope (vertical section). Impact of an avalanche on a building (horizontal section).
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